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Senin, 01 Desember 2014

Konsentrasi obat dan dosis untuk pengobatan bakteri atau jamur keratitis

Tabel 2: Konsentrasi obat dan dosis untuk pengobatan bakteri atau jamur keratitis.


Obat
Topikal
Subkonjuntival
Sistemik
Amikacin
50 – 100 mg/mL
25 mg/0.5 mL/dose
10 -15 mg/kg/d in two or three doses
Amphotericin
1.5 – 3 mg/mL
0.5 -1 mg

Carbenicillin
4 mg/mL
125 mg / 0.5 mL/dose
100-200 mg/kg/d IV in four doses
Cefazolin
50 mg/mL
100 mg / 0.5 mL/dose
15 mg/kg/d IV in four doses
Ceftazidime
50 mg/mL
250 mg (0.5 mL)
1 g IV or IM every 8-12 hours (adult dose)
Ceftriaxone


1 -2 g/d IV or IM
Ciprofloxacin
0.3 % solution

250 -500 mg orally in four doses
Flucytosine
1 % solution

50 – 150 mg/kg/d orally in four doses
Gentamicin
10 -20 mg/mL
20 mg/0.5 – 1 mL/dose

Miconazole
1% solution atau 2% oitment
5-10 mg; 0.5-1mL/dose

Natamycin
5 % suspension


Neomycin
20 mg/mL


Nystatin
50,000 unit/mL atau cream (100,000unit/g)


Paromomyocin
10 mg/mL


Penicillin G
100,000 unit/mL
1 million unit/dose
40,000-50,000 units/kg IV in four doses; or continously, 2-6 million units IV every 4-6 hours
Polyhexamethylene biguanide
0.01%-0.02% solution


Polymyxin B
1-2 mg/mL
10 mg/0.5 mL dose

Propamidine
0.1 mg/mL solution; 0.15% oitment


Tobramycin
10-20 mg/mL
20 mg/0.5 mL/dose

Vancomycin
50 mg/mL
25 mg/ 0.5 mL/dose